NOTE: This trial has now ended. Results to follow.
We are delighted to announce that The Functional Gut Clinic will shortly be embarking on a novel Clinical Trial to look at the relationship between colonic pH and symptoms in IBS patients. Our previously published work (Caecal pH in IBS pdf) using the Wireless Motility Capsule (SmartPill) has shown that the proximal colonic pH is lower in IBS patients with bloating, distension and an alternating bowel habit when compared to healthy controls.
This image shows a typical SmartPill trace with pressure in red, temperature in blue and pH in green. This particular tracing shows a stable pH in the ileum followed by a sharp drop as the capsule moves into the caecum. This pH drop is due to bacterial fermentation of undigested food. The capsule unusually moves back into the Ileum in this patient who was subsequently shown to have Small Intestinal Bacterial Overgrowth (SIBO).