Groundbreaking clinical trials

from our team of specialist researchers

We’re driving developments in digestive health by conducting research studies that will shape the future.

Apply to take part in our upcoming clinical trials, or sign up to be the first to hear about new studies.

ⓘ If you’re a company with a gut health product and you’d like to explore running your own research trial with us,

find out more here.

At The Functional Gut Clinic, we’re dedicated to conducting robust and innovative clinical studies in gut health.

Gut issues affect more than 80% of us at some point - and they have a big impact on our quality of life.

We work hard to advance the science, put products to the test and improve the lives of people suffering with gut symptoms.

This is your opportunity to be part of innovative research and change the future of treatments.

Ready to get involved in our research?

Our current clinical trials

*currently recruiting*

IBS-D

and Leaky gut

What the study is about

Investigating the effects of a food supplement (two natural compounds) on gut barrier function.

Who can take part

  • People with symptoms of IBS with diarrhoea

  • Located in the UK and able to come to clinic in person

What’s involved

  • Visit Manchester clinic in person 3 times

  • Take 1 capsule daily for 3 weeks

  • Complete a daily bowel diary

  • Duration: ~ 5 weeks

Compensation

Remunerated for travel and time

IBS-D

(Vitamin D, Curcumin, and Green Tea)

What the study is about

Investigating the effects of a combined food supplement to see whether it could benefit IBS-D sufferers (compared to a placebo).

Who can take part

  • Symptoms of IBS with diarrhoea

  • Live in UK

    (able to complete remote)

What’s involved

  • Visit the clinic in-person 4 times over ~ 10 weeks

  • Take the study capsules as directed for 8 weeks

  • Complete daily bowel diaries

  • Duration: ~ 10 weeks

Compensation

Remunerated for travel and time

PelviPower

Faecal Incontinence

What the study is about

Investigating the effect of magnetic stimulation on the pelvic floor as a treatment for faecal incontinence.

Who can take part

  • Female

  • 18 years or older

  • Had faecal incontinence for more than 6 months

  • Live in the UK, able to come in clinic (London)

What’s involved

  • Attend 10 treatment sessions twice a week

  • Attend 12 visits in total over a 10 weeks

  • Duration: ~ 10 weeks trail period/ ~ 3 month follow up call post trial.

Compensation

Remunerated for travel and time

All trials have been approved by an independent research ethics committee and are completed in accordance with good clinical practice.

Hear from previous participants

"A huge thank you to Jess, Sam, Jordan and Katie. They are so patient, kind and helpful. A particular shoutout to Katie for doing painless blood tests!"

Completed clinical trials

read about our previous clinical trials

Constipation

and ERME™

What the study was about

Investigating enzyme-rich malt extract (ERME™) for the treatment of chronic constipation.

Who took part in the study

  • People with symptoms of IBS with diarrhoea

What the study involved

Gave 20 individuals with constipation the enzyme-rich malt extract (around 1 tablespoon with food for 4 weeks twice a day)

Overview of findings

Taking ERME appeared to help constipation and reduce daily symptoms of abdominal pain and bloating.

Reflux Testing

and structural Gaviscon regime

What the study was about

Exploring whether a structural Gaviscon regime helps individuals manage symptoms prior to reflux testing after stopping acid suppression therapy.

Who took part in the study

  • Individuals with acid reflux symptoms

What the study involved

Individuals randomised to a scheduled Gaviscon regime or standard prep prior to reflux testing took Gaviscon liquid for 4 times per day

Overview of findings

The individuals taking the structured regimen of Gaviscon experienced less symptoms.

Probiotics

effects on the microbiome

What the study was about

Investigating the effects of probiotics in the microbiome of healthy people

Who took part in the study

  • 41 healthy adults

What the study involved

We gave 41 healthy adults a multi-strain probiotic for 8 weeks and looked at the gut microbiome before and after.

Overview of findings

The probiotic supplementation did not change the overall diversity of the gut microbiome in our healthy adults, some changes in functional pathways of the gut microbiome were seen.

Do you have a product you want to prove?

Our team at The Functional Gut Clinic are the leading accredited experts in running clinical and lifestyle trials. If you are interested in getting gold standard research and solid scientific evidence for your product, get in touch to find out how we can help.

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