Groundbreaking clinical trials
from our team of specialist researchers
We’re driving developments in digestive health by conducting research studies that will shape the future.
Apply to take part in our upcoming clinical trials, or sign up to be the first to hear about new studies.
ⓘ If you’re a company with a gut health product and you’d like to explore running your own research trial with us,
find out more here.
At The Functional Gut Clinic, we’re dedicated to conducting robust and innovative clinical studies in gut health.
Gut issues affect more than 80% of us at some point - and they have a big impact on our quality of life.
We work hard to advance the science, put products to the test and improve the lives of people suffering with gut symptoms.
This is your opportunity to be part of innovative research and change the future of treatments.
Ready to get involved in our research?
Our current clinical trials
*currently recruiting*
Reflux
What the study is about
Investigating two different treatment approaches for reflux symptoms.
Who can take part
People living with symptoms of heartburn and regurgitation.
Located in the UK, able to come to clinic in person.
What’s involved
6 appointments over a 6 month period - 3 in person visits and 3 remote appointments.
Compensation
You will be paid for your time and travel expenses.
Constipation
Multi-Strain Bacterial Food
What the study is about
We’re conducting a trial looking at a multi-strain bacterial food product that may benefit symptoms of constipation.
Who can take part
Male or non-pregnant female
18-70 years old
Live in the UK, able to come in clinic (London)
Able to attend 3 in person visits to our London clinic
What’s involved
Attend three in person visits to our London Clinic.
Take the supplement we provide
Undergo Gut Transit studies and breath tests
Compensation
Remunerated for travel and time
PelviPower
Faecal Incontinence
What the study is about
Investigating the effect of magnetic stimulation on the pelvic floor as a treatment for faecal incontinence.
Who can take part
Female
18 years or older
Had faecal incontinence for more than 6 months
Live in the UK, able to come in clinic (London)
What’s involved
Attend 10 treatment sessions twice a week
Attend 12 visits in total over a 10 weeks
Duration: ~ 10 weeks trail period/ ~ 3 month follow up call post trial.
Compensation
Remunerated for travel and time
IBS
Vagus Nerve Stimulation
What the study is about
We’re trialling a device that clips to the ear and stimulates the vagus nerve which may help manage symptoms of IBS.
Who can take part
Male or non-pregnant female
18 - 70 years old
Live in the UK, able to come in clinic (Manchester only)
What’s involved
1 in person visits to our Manchester clinic
2 phone call appointments
Complete a daily diary - for 6 weeks
Try the device at home daily - for 4 weeks
Compensation
Remunerated for travel and time
Healthy Participants
No underlying health conditions
What the study is about
We are looking at the effect of a longevity supplement on markers of cellular health, ageing and general wellbeing.
Who can take part
Male or non-pregnant female
35 or older
Able to come in clinic to Manchester twice
What’s involved
Attend two in Clinic visits.
Take a vitamin supplement for 1 month.
Compensation
You will be compensated for your time.
All trials have been approved by an independent research ethics committee and are completed in accordance with good clinical practice.
Hear from previous participants
"A huge thank you to Jess, Sam, Jordan and Katie. They are so patient, kind and helpful. A particular shoutout to Katie for doing painless blood tests!"
Completed clinical trials
read about our previous clinical trials
Constipation
and ERME™
What the study was about
Investigating the effects of a food supplement (two natural compounds) on gut barrier function.
Who took part in the study
People with symptoms of IBS with diarrhoea
What the study involved
Gave 20 individuals with constipation the enzyme-rich malt extract (around 1 tablespoon with food for 4 weeks twice a day)
Overview of findings
Taking ERME appeared to help constipation and reduce daily symptoms of abdominal pain and bloating.
Reflux Testing
and structural Gaviscon regime
What the study was about
Exploring whether a structural Gaviscon regime helps individuals manage symptoms prior to reflux testing after stopping acid suppression therapy.
Who took part in the study
Individuals with acid reflux symptoms
What the study involved
Individuals randomised to a scheduled Gaviscon regime or standard prep prior to reflux testing took Gaviscon liquid for 4 times per day
Overview of findings
The individuals taking the structured regimen of Gaviscon experienced less symptoms.
Probiotics
effects on the microbiome
What the study was about
Investigating the effects of probiotics in the microbiome of healthy people
Who took part in the study
41 healthy adults
What the study involved
We gave 41 healthy adults a multi-strain probiotic for 8 weeks and looked at the gut microbiome before and after.
Overview of findings
The probiotic supplementation did not change the overall diversity of the gut microbiome in our healthy adults, some changes in functional pathways of the gut microbiome were seen.
IBS-D
and leaky gut
What the study was about
Investigating enzyme-rich malt extract (ERME™) for the treatment of chronic constipation.
Who took part in the study
People with symptoms of IBS with diarrhoea
Located in the UK and able to come to clinic in person
What the study involved
Visit Manchester clinic in person 3 times
Take 1 capsule daily for 3 weeks
Complete a daily bowel diary
Duration: ~ 5 weeks
Overview of findings
The study found that a 3-week supplementation with NCT/NFT significantly improved gut barrier function and reduced abdominal distension in IBS-D patients, indicating both objective and subjective benefits without adverse effects.
Do you have a product you want to prove?
Our team at The Functional Gut Clinic are the leading accredited experts in running clinical and lifestyle trials. If you are interested in getting gold standard research and solid scientific evidence for your product, get in touch to find out how we can help.
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