ALL TEST ARE ACCREDITED & REGULATED BY


Heartburn is a burning pain in your chest. This pain is caused by stomach acid rising from your stomach into your oesophagus (the pipe that takes food from your mouth to your stomach).
This can cause:
- Burning pain in the middle of your chest
- Pain which is worse when you bend over or lie down
- Burning pain that radiates into your back
By learning more about the causes of, tests for, and treatment for heartburn, you can understand it better and make informed decisions to get back on track.

There are several possible causes of heartburn, and it’s important to find out what’s causing yours.
Here are the main causes of heartburn:
Gastroesophageal reflux disease (GORD)
Hiatus hernia, when part of your stomach moves up into your chest
Surgery you’ve had in the past (especially bariatric surgery)
Certain foods and drinks, such as alcohol, coffee, chocolate, and fatty or spicy foods
Being overweight
Smoking
Pregnancy
Stress or anxiety
Medication, such as anti-inflammatory painkillers
Overgrowth of bacteria in your small intestine (this is called SIBO)


Diagnostic testing allows us to pinpoint the exact cause so we can recommend the right solution.
At the Functional Gut Clinic, we use the following highly accurate and trusted diagnostic tools, to identify the underlying cause of your heartburn:
Oesophageal manometry – which measures the function of your oesophagus (food pipe)
24-hour pH impedance monitoring – which looks at whether you have any reflux
Carbohydrate malabsorption breath test – which finds out if you have certain food intolerances (lactose or fructose)
Small intestinal bacterial overgrowth (SIBO) breath test – which finds out if you have an overgrowth of bacteria in your small intestine (called SIBO)
Gastric emptying test – which measures how quickly food leaves your stomach

Gastroesophageal reflux disease, or GERD, is a medical condition where acid from the stomach persistently backflows into the oesophagus. Most people experience occasional acid reflux or heartburn. In GERD, however, these episodes happen several times a week or more.
GERD is often thought of as a fixed condition. However, it’s actually a progressive one, as symptoms often worsen quietly over time. Understanding the different stages of GERD is critical to reversing the condition and preventing the worst effects of acid reflux.
Below, we cover the 4 stages of GERD, how it progresses, and when it’s time to consider professional reflux testing and evaluation.
GERD is primarily caused by a weakening of the lower oesophageal sphincter (LOS). This sphincter forms the junction between the oesophagus and the stomach, preventing backflow from occurring. However, certain foods and other conditions can cause this muscle to weaken.
Other factors exacerbating GERD include:
Frequent acid exposure to the oesophagus
Large or late evening meals
Trigger foods (fatty foods, spicy foods, caffeine, alcohol, chocolate)
Poor posture and slouching after meals
Excess abdominal pressure (tight clothing, weight gain)
Delayed stomach emptying
Chronic stress
The first stage of GERD is mild, occasional reflux. People may notice heartburn, mild chest pain, a lump sensation in the throat (globus), and the regurgitation of food or liquid. Exposure is minimal, meaning there is no visible oesophageal damage.
Most people stay at this stage or find some relief. It can last for years. But it’s an early warning sign many people ignore. Usually, stage 1 GERD is relieved by posture, smaller meals, or antacids.
Stage 2 GERD increases the number of acidity attacks per week. At this stage, people often notice symptoms multiple times per week, including nighttime reflux and sleep disturbance.
Regurgitation, chronic throat clearing, and cough is common. The repeated acid exposure triggers early inflammation of the oesophagus. At this stage, lifestyle changes alone may no longer be enough. Medication can become necessary, at least in the short term, to allow the oesophageal lining to heal.
Stage 3 GERD presents with daily symptoms. Patients complain of painful swallowing (odynophagia), food “getting stuck” (dysphagia), and regular heartburn. Due to the increased prevalence of symptoms, there’s an increased dependence on medication.
Long-term exposure to acid has created persistent, confirmed oesophageal inflammation or erosion. At this stage, the risk of complications is significantly higher, and the impact on quality of life becomes increasingly severe.
Stage 4 is the most advanced stage of GERD. Patients experience long-term damage to the oesophagus, including oesophageal strictures, Barrett’s oesophagus, and even an increased risk of oesophageal cancer in some cases.
The symptoms also progress to chronic chest pain, swallowing issues (dysphagia), and unintentional weight loss. Specialist management is required at this stage.
If GERD isn’t treated, it will naturally progress. The advanced stages occur after prolonged acid exposure. This can lead to:
Oesophageal damage and narrowing: Long-term acid exposure can cause inflammation and scarring, making swallowing painful and increasing the risk of food becoming stuck.
Barrett’s oesophagus and cancer risk: Repeated injury to the oesophageal lining can trigger cell changes that can raise the long-term risk of oesophageal cancer.
Nutritional and weight problems: Pain with eating can lead to food avoidance, causing unintentional weight loss and nutrient deficiencies.
Chronic fatigue and reduced quality of life: Ongoing pain, broken sleep, and anxiety around food can significantly affect daily energy, mood, and overall wellbeing.
In short, yes.
Stages 1-2 are highly reversible, especially with lifestyle changes. Either with a small amount of medication or lifestyle changes alone, you can relieve the inflammation and reduce symptoms overall.
Stage 3 is a little more difficult. However, with persistent medication and lifestyle changes, inflammation can improve with targeted treatment.
Stage 4, on the other hand, often results in permanent damage. However, progression can be slowed, and related complications are often treatable.
GERD doesn’t have to be something you manage forever. With the right intervention, you can reverse reflux, soothe your oesophagus, and return to normal, especially in the early stages.
The most important step is understanding exactly what’s driving your reflux and how advanced it really is.
The Functional Gut Clinic offers advanced 24-hour reflux testing and specialist assessments to diagnose the true cause of your symptoms. Don’t supress them or dismiss them as part of normal life. Learn more about our services and get clear answers that could help prevent serious complications further down the line.
The upcoming article might interest you: The upcoming article might interest you
Heartburn is often experienced after eating and can last anywhere from a few minutes to several hours. The stomach releases more acid after eating certain foods, including spicy dishes, fatty foods, citrus fruits, tomato-based products, garlic, and caffeinated drinks. The more acid that is produced, the greater the risk of heartburn.
Other factors include obesity, smoking, stress, pregnancy, and eating too close to bedtime.



Heartburn primarily causes an uncomfortable or burning sensation in the middle of your chest. You may also experience:
A burning sensation in your throat
A strong acidic or sour taste in your mouth
Difficulty swallowing (dysphagia)
A feeling of pressure or pain behind your breastbone
Repeated coughing
Hoarse voice
In addition to these symptoms, the pain from the acid can get worse when lying down or bending over. This is because the acid flows out of the stomach and into the oesophagus. Whenever you lie down, you increase the risk of heartburn-related symptoms.
Constant heartburn is a sign of a severe underlying condition. Most people experience heartburn in episodic attacks – usually after consuming certain foods. If the heartburn is persistent, it’s crucial to speak to a medical professional. You can also consider organising a test via The Functional Gut Clinic (see below).


Heartburn occurs when the contents of the stomach enter the oesophagus (the food pipe connecting your stomach to your throat). Usually, the stomach contents are prevented from going back into the oesophagus by a juncture called the lower oesophageal sphincter. However, in some people, this sphincter doesn’t function properly.
Heartburn is a symptom of gastroesophageal reflux disease (GORD). GORD simply refers to the backflow of acid from the stomach into the oesophagus. GORD is the condition; heartburn is the symptom.

Several factors increase the risk of heartburn. The causes of heartburn and GORD either increase acid production within the stomach or affect the functioning of the lower oesophageal sphincter. These include:
Hiatal hernia. A hiatus hernia involves a part of your upper stomach penetrating through the diaphragm (the layer of muscle separating your chest from your stomach). This usually occurs due to a weakness or tear.
Pregnancy. If you become pregnant, the increased pressure during the third trimester (and sometimes earlier) forces the stomach contents backwards, causing heartburn.
Surgery. Previous surgery, especially bariatric surgery, increases the risk of not only heartburn but also a hiatus hernia.
Smoking. Smoking is closely linked to heartburn and GORD. People who quit smoking notice a significant reduction in heartburn symptoms.


Overweight or obesity. Being overweight or obese is a major risk factor for GORD. This is likely due to the increased pressure in the stomach alongside a diet high in fatty, processed foods.
Medications. Certain medications, such as anti-inflammatory painkillers (e.g., ibuprofen or aspirin), sedatives, and blood pressure medications, can increase your risk of heartburn.
Stress or anxiety. An increase in stress or anxiety can increase acid production in some people, leading to heartburn. It’s often accompanied by another factor.
Small intestine bacterial overgrowth (SIBO). Excessive bacterial growth in the small intestine leads to increased abdominal pressure and subsequent acid reflux, which can cause heartburn. Managing SIBO often reduces these symptoms.
Acid production is a normal part of the stomach’s function. The acid helps digest food. Certain foods require more acid to digest, triggering an increased production in the stomach.
For most people, this isn’t an issue as the acid flows into the small intestine. However, if you struggle with heartburn and GORD, then it’s sensible to limit or avoid certain foods. These include:
Citrus fruits (like oranges and grapefruits)
Tomatoes and tomato-based products
Spicy foods
Garlic and onions
Chocolate
Mint
Fatty or fried foods
Caffeinated beverages (such as coffee and tea)
Carbonated drinks
Alcohol
It’s not just the food. Eating an excessively large meal, wearing tight clothes, and lying down soon after eating can increase the risk of heartburn. If you’re experiencing persistent heartburn, it’s often linked to diet rather than another factor.

No. Heartburn specifically refers to the burning sensation in the chest. GORD is the underlying condition involving the backflow of acid. Heartburn is a symptom of GORD. Acid reflux is sometimes used as shorthand for GORD – however, not every attack of acid reflux is an example of GORD.
Acid reflux refers to any episode of acid backflowing into the oesophagus. If the episodes occur two or more times a week, it is diagnostic for GORD. Most people experience acid reflux episodes occasionally. This can increase in frequency as acid reflux progresses to GORD. You should speak to a doctor if you notice this change.

Heartburn is always caused by the backflow of acid into the oesophagus. Several other conditions can create a similar sensation. For example:
Oesophageal ulcers. Ulcers occur due to erosion of the oesophageal lining. Often associated with acid reflux or overusing anti-inflammatory medications.
Oesophagitis. Severe inflammation of the oesophagus is closely linked to GORD. However, it can also be caused by medications and infections. An allergic condition known as eosinophilic oesophagitis can also cause heartburn.
Functional heartburn. Unlike the other conditions, this isn’t a problem with your oesophagus or stomach. It’s caused by a disorder of the gut-brain connection. It involves the same heartburn symptoms but without any signs of acid reflux or inflammation. It’s connected to overactive nerves.


Heartburn is not a permanent condition. It lasts as long as the acid is present to irritate the oesophagus and throat. Most people experience heartburn and GORD for between a few minutes to several hours. The timespan often depends on the underlying cause. For example, if your heartburn is due to your diet, it might go away within a few minutes. In contrast, if you have a hiatus hernia, the heartburn might persist for much longer, even after standing up.
Constant heartburn is a rare symptom. It’s a concerning sign, as the acid can continue to damage your oesophagus. If you’re constantly feeling heartburn (or using lots of antacids), then it’s critical to speak to a doctor.
Most cases of heartburn aren’t serious. It’s common to experience heartburn after a large meal or eating certain foods. However, if the heartburn becomes repeated or constant, it can cause long-term damage. Usually, the damage caused by acid reflux heals like any injury. If it happens regularly, then the oesophagus lining can become permanently injured.
Potential long-term complications include:
Oesophageal strictures. The lining of the oesophagus becomes replaced with scar tissue due to repeated inflammation. This scar tissue causes a narrowing of the oesophagus (stricture), which prevents food from getting through.
Intestinal metaplasia. The tissue lining of the oesophagus undergoes a change to look more like the lining of your intestines, protecting it from damage. It is called Barrett’s oesophagus and is a precancerous condition.
Oesophageal cancer. Cancer is a rare complication of GORD and heartburn. It occurs due to persistent inflammation and cellular changes. The longer your heartburn persists, the greater the risk of cancer.
Heartburn and GORD can also indicate problems in your stomach. For example, excess acid production can lead to gastritis (stomach inflammation) and stomach ulcers. It may also aggravate preexisting conditions such as asthma.

The following tests may be used to diagnose what is causing your heartburn:
Oesophageal manometry – which measures the function of your oesophagus (food pipe)
24-hour pH impedance monitoring – which looks at whether you have any reflux
Carbohydrate malabsorption breath test – which finds out if you have certain food intolerances (lactose or fructose)
Small intestinal bacterial overgrowth (SIBO) breath test – which finds out if you have an overgrowth of bacteria in your small intestine (called SIBO)
Gastric emptying test – which measures how quickly food leaves your stomach
The following tests may be used to diagnose what is causing your heartburn:
Oesophageal manometry – which measures the function of your oesophagus (food pipe)
24-hour pH impedance monitoring – which looks at whether you have any reflux
Carbohydrate malabsorption breath test – which finds out if you have certain food intolerances (lactose or fructose)
Small intestinal bacterial overgrowth (SIBO) breath test – which finds out if you have an overgrowth of bacteria in your small intestine (called SIBO)
Gastric emptying test – which measures how quickly food leaves your stomach

Most people who experience occasional heartburn symptoms can benefit from lifestyle changes. This involves limiting exposure to potential triggers. You might want to try:
Avoiding trigger foods, such as fatty foods or caffeinated beverages
Eating smaller meals
Avoiding tight clothing
Avoiding lying down immediately after eating
Quitting smoking and alcohol consumption.
Often, people find that small changes to their diet can stop or reduce episodes of heartburn. If the heartburn continues, it’s usually a sign that something else is going on. It’s crucial to get to the bottom of your symptoms; otherwise, they will persist.



As heartburn is caused by acid, neutralising this acid relieves symptoms. The primary treatment for heartburn is an over-the-counter (OTC) antacid, such as Gaviscon or Alka-Seltzer. These medications provide immediate relief from your symptoms – perfect for tackling a sudden acid reflux attack. If you experience constant heartburn, it’s sensible to carry antacids with you. However, excessive use of antacids can cause other problems.
Your doctor may prescribe medications that prevent acid production. This includes:
Proton Pump Inhibitors (PPIs). These medications reduce stomach acid production by blocking the enzyme in the stomach lining that produces acid. Common examples include omeprazole, esomeprazole, and pantoprazole. PPIs are used to treat GORD by allowing the oesophagus to heal and preventing further damage.
H2 Receptor Antagonists. These drugs work by blocking H2 receptors on stomach cells that signal the production of acid. This results in decreased stomach acid output. Examples include ranitidine, famotidine, and cimetidine. They are effective in relieving GORD symptoms and are generally used for milder cases.

In the majority of cases, lifestyle changes and medication are enough to prevent heartburn symptoms. If GORD doesn’t respond to medication, surgery might be a potential option. This can repair a hiatus hernia, strengthening the lower oesophageal sphincter and permanently preventing the backflow of acid.
Procedures include:
Nissen fundoplication. This procedure tightens the junction between the stomach and the oesophagus.
Transoral incisionless fundoplication. A similar procedure performed non-surgically using an endoscope.
LINX device. A tiny ring of magnets is placed around the junction between the stomach and oesophagus to prevent reflux. It’s a type of minimally invasive surgery.
Heartburn is extremely uncomfortable. However, most cases are relatively mild and treatable with antacids. Speak to a medical professional if:
You experience heartburn more than once a week
You have other associated symptoms
You have difficulty swallowing
Your heartburn persists despite treatment
You’re over the age of 60
You have a tight or squeezing chest pain
You cough up blood
Remember, occasional heartburn is relatively normal. But if you have constant heartburn, it’s crucial to get tested. The Functional Gut Clinic is highly experienced in diagnosing acid reflux. We’ll organise your test and provide advice on what to do next.

"Very professional while welcoming and friendly"
"The manner and demeanour of all staff from reception to people carrying out the test was very professional but welcoming and friendly. Atmosphere is very relaxed and all instructions clear and concise."
London Patient

"Highly recommend this"
"Thanks to Dr Hobson and everyone at the Functional Gut Clinic. The whole team is very kind and generous and they are doing things that are cutting edge and they actually get results."
Manchester Patient

"Highly recommend this"
"After stopping my lansoprazole, every time I had a warm drink, I could feel it burn all the way down to my stomach. Thank you to Sam for making me feel at ease." - Manchester Patient

"My experience could not be better"
"Pleasant and knowledgeable staff that made the experience more enjoyable than it should be!" - London Patient

"Very friendly and knowledgeable"
"An excellent service from beginning to end. I would recommend to anyone who was considering having testing done. Very friendly and knowledgeable!" - Manchester Patient

"Very kind and helpful"
"It was also great to have time to talk to the clinicians – very important when you have problems. Reception staff also very kind and helpful." - Manchester Patient


Burning mid-chest, worse when bending or lying down

Difficulty going to the toilet, unusual stools, often with stomach ache or intestinal cramps, bloating, nausea or appetite loss

Feeling uncomfortably full and tight, excess belching/breaking wind, abdominal pain or gurgling

Bringing food or drink back up, difficulty swallowing, feeling that food or drink is stuck in your throat, horrible taste in your mouth

Dysphagia - difficulty swallowing, feeling that food or drink is stuck in your throat, horrible taste in your mouth

Loose or explosive stools, can’t get to a toilet in time

Cramps; sharp or dull pain, Bloating, Excessive belching, Nausea or vomiting

Stools leak unexpectedly, Can’t get to a toilet in time

Abdominal pain or cramping, bloating, changes in bowel habits and urgency, gas