Heartburn

Struggling with heartburn? Here’s what you need to know to find relief.

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What is heartburn?

Heartburn is a burning pain in your chest. This pain is caused by stomach acid rising from your stomach into your oesophagus (the pipe that takes food from your mouth to your stomach).

This can cause:

- Burning pain in the middle of your chest

- Pain which is worse when you bend over or lie down

- Burning pain that radiates into your back

By learning more about the causes of, tests for, and treatment for heartburn, you can understand it better and make informed decisions to get back on track.

Why does heartburn happen?

There are several possible causes of heartburn, and it’s important to find out what’s causing yours.

Here are the main causes of heartburn:

  • Gastroesophageal reflux disease (GORD)

  • Hiatus hernia, when part of your stomach moves up into your chest

  • Surgery you’ve had in the past (especially bariatric surgery)

  • Certain foods and drinks, such as alcohol, coffee, chocolate, and fatty or spicy foods

  • Being overweight

  • Smoking

  • Pregnancy

  • Stress or anxiety

  • Medication, such as anti-inflammatory painkillers

  • Overgrowth of bacteria in your small intestine (this is called SIBO)

Diagnosing heartburn

Diagnostic testing allows us to pinpoint the exact cause so we can recommend the right solution.

Oesophageal manometry, 24-hour pH, malabsorption breath tests, SIBO & gastric emptying

At the Functional Gut Clinic, we use the following highly accurate and trusted diagnostic tools, to identify the underlying cause of your heartburn:

  • Oesophageal manometry – which measures the function of your oesophagus (food pipe)

  • 24-hour pH impedance monitoring – which looks at whether you have any reflux

  • Carbohydrate malabsorption breath test – which finds out if you have certain food intolerances (lactose or fructose)

  • Small intestinal bacterial overgrowth (SIBO) breath test – which finds out if you have an overgrowth of bacteria in your small intestine (called SIBO)

  • Gastric emptying test – which measures how quickly food leaves your stomach

Learn more about heartburn

How to Read Your Gut Microbiome Test Results

How to Read Your Gut Microbiome Results

April 10, 20264 min read

You’ve decided to get a gut microbiome test to support your gut health. You’ve sent off your sample, received your results, only to find you don’t understand a word of what’s written. That’s perfectly normal. Depending on the type of microbiome test, interpreting the results can be confusing.

The results may contain charts, percentages, and unfamiliar bacterial names. Unless you know your Lactobacilli from your Clostridium, you’re likely to be left scratching your head.

Below, we cover what your gut microbiome test results mean, how to interpret them, and how they should guide your lifestyle or dietary improvements.

What a Gut Microbiome Test Actually Measures

A gut microbiome test usually refers to a stool microbiome analysis. The stool sample undergoes DNA sequencing to detect the presence and proportions of different gut bacteria.

The test typically measures:

  • Bacterial diversity

  • Beneficial vs harmful bacterial species

  • Microbial balance

  • Functional markers (sometimes)

But it’s not the only type of gut microbiome test. Your doctor might recommend SIBO testing, hydrogen sulphide testing, and more, which are all related to the gut microbiome. However, none of these tests provide a comprehensive assessment of the bacterial species or microbiome composition.

Understanding Microbial Diversity

Diversity is one of the most important metrics of your gut microbiome. It’s not just about what specific species live in your gut, but how many different ones there are. Studies show that higher diversity is linked to better metabolic health, stronger immune function, and resilience to disease.

Why? Well, each beneficial bacterial species provides a specific service. The more species you have, the more services you benefit from. Plus, with many different species, it prevents any one species from dominating.

In a stool microbiome analysis, it’s reported as an alpha diversity score or diversity index.

Unfortunately, poor diet, antibiotic use, stress, or illness can all harm your bacterial diversity. It can lower beneficial bacteria numbers, which may open the door for harmful species to take over.

Beneficial vs Potentially Harmful Bacteria

Diversity is only one metric. The next is the balance between different kinds of bacteria. Here, we start digging down into the specific species. Generally, we group bacteria into two categories:

  1. Beneficial bacteria, such as Bifidobacterium and Lactobacillus, which support digestion, metabolic health, and other essential functions.

  2. Opportunistic bacteria are fine in small numbers but become problematic when they overgrow.

There’s also a third category: pathogenic bacteria. They’re rarely present in healthy microbiomes but are responsible for certain diseases.

Relative Abundance: What the Percentages Mean?

Relative abundance is how common each group of bacteria is relative to others. It’s usually shown in charts or pie graphs. Think of it as the percentage of different bacterial groups in your sample.

For example, a report might show that certain groups make up 30% of your microbiome, while others account for smaller proportions.

Your report might compare your results with population averages or reference ranges. So, you’ll understand how your microbiome compares with others. It’s best not to take this part too seriously though, as everyone’s microbiome is unique.

Key Functional Markers in Some Reports

Advanced microbiome tests might go a step further, identifying bacteria and estimating how your gut microbes function metabolically. These tests might look at:

  • Short-chain fatty acid production – Indicates how well your microbes produce beneficial compounds, such as butyrate which supports the gut lining.

  • Fibre fermentation – Shows how effectively bacteria break down dietary fibre into useful metabolites.

  • Inflammatory markers – Highlights microbial patterns sometimes linked to gut inflammation or imbalance.

  • Bile acid metabolism – Reflects how gut bacteria help process bile acids involved in digestion.

Common Patterns Seen in Microbiome Results

Low Diversity

Low diversity means a few species or groups of bacteria dominate your gut. This is often linked to low fibre intake, repeated antibiotic use, or a diet high in ultra-processed foods.

High Opportunistic Bacteria

Opportunistic bacteria tend to proliferate due to poor diet, stress, or a gut imbalance. You may have noticed symptoms like bloating or constipation.

Low Beneficial Bacteria

Low levels of beneficial bacteria usually go hand in hand with high levels of opportunistic bacteria. It’s a common pattern seen in Western diets, where processed foods, not whole foods, dominate.

Using Your Results to Improve Your Gut Health

Bad results aren’t a moment to despair; it’s an opportunity to build a healthier gut. The Functional Gut Clinic provides personalised recommendations based on the gut microbiome results you receive from us to optimise your gut microbiome.

Often, our recommendations focus on:

  • Fibre-rich foods

  • Fermented foods

  • Low-stress lifestyle changes

Learn more about how personalised microbiome testing can help you understand your gut health and take practical steps to improve it. And feel free to take a look at all we offer within our Microbiome Clinic.

You may find the following article interesting to read: How Your Gut Bacteria Can Influence Your Weight

gut microbiome test resultshow to interpret microbiome results
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Heartburn is a burning pain in your chest.

Heartburn is often experienced after eating and can last anywhere from a few minutes to several hours. The stomach releases more acid after eating certain foods, including spicy dishes, fatty foods, citrus fruits, tomato-based products, garlic, and caffeinated drinks. The more acid that is produced, the greater the risk of heartburn.

Other factors include obesity, smoking, stress, pregnancy, and eating too close to bedtime.

What are the symptoms of heartburn?

Heartburn primarily causes an uncomfortable or burning sensation in the middle of your chest. You may also experience:

  • A burning sensation in your throat

  • A strong acidic or sour taste in your mouth

  • Difficulty swallowing (dysphagia)

  • A feeling of pressure or pain behind your breastbone

  • Repeated coughing

  • Hoarse voice

In addition to these symptoms, the pain from the acid can get worse when lying down or bending over. This is because the acid flows out of the stomach and into the oesophagus. Whenever you lie down, you increase the risk of heartburn-related symptoms.

Constant heartburn is a sign of a severe underlying condition. Most people experience heartburn in episodic attacks – usually after consuming certain foods. If the heartburn is persistent, it’s crucial to speak to a medical professional. You can also consider organising a test via The Functional Gut Clinic (see below).

What causes heartburn?

Heartburn occurs when the contents of the stomach enter the oesophagus (the food pipe connecting your stomach to your throat). Usually, the stomach contents are prevented from going back into the oesophagus by a juncture called the lower oesophageal sphincter. However, in some people, this sphincter doesn’t function properly.

Heartburn is a symptom of gastroesophageal reflux disease (GORD). GORD simply refers to the backflow of acid from the stomach into the oesophagus. GORD is the condition; heartburn is the symptom.

Several factors increase the risk of heartburn. The causes of heartburn and GORD either increase acid production within the stomach or affect the functioning of the lower oesophageal sphincter. These include:

  • Hiatal hernia. A hiatus hernia involves a part of your upper stomach penetrating through the diaphragm (the layer of muscle separating your chest from your stomach). This usually occurs due to a weakness or tear.

  • Pregnancy. If you become pregnant, the increased pressure during the third trimester (and sometimes earlier) forces the stomach contents backwards, causing heartburn.

  • Surgery. Previous surgery, especially bariatric surgery, increases the risk of not only heartburn but also a hiatus hernia.

  • Smoking. Smoking is closely linked to heartburn and GORD. People who quit smoking notice a significant reduction in heartburn symptoms.

  • Overweight or obesity. Being overweight or obese is a major risk factor for GORD. This is likely due to the increased pressure in the stomach alongside a diet high in fatty, processed foods.

  • Medications. Certain medications, such as anti-inflammatory painkillers (e.g., ibuprofen or aspirin), sedatives, and blood pressure medications, can increase your risk of heartburn.

  • Stress or anxiety. An increase in stress or anxiety can increase acid production in some people, leading to heartburn. It’s often accompanied by another factor.

  • Small intestine bacterial overgrowth (SIBO). Excessive bacterial growth in the small intestine leads to increased abdominal pressure and subsequent acid reflux, which can cause heartburn. Managing SIBO often reduces these symptoms.

Foods to avoid

Acid production is a normal part of the stomach’s function. The acid helps digest food. Certain foods require more acid to digest, triggering an increased production in the stomach.

For most people, this isn’t an issue as the acid flows into the small intestine. However, if you struggle with heartburn and GORD, then it’s sensible to limit or avoid certain foods. These include:

  • Citrus fruits (like oranges and grapefruits)

  • Tomatoes and tomato-based products

  • Spicy foods

  • Garlic and onions

  • Chocolate

  • Mint

  • Fatty or fried foods

  • Caffeinated beverages (such as coffee and tea)

  • Carbonated drinks

  • Alcohol

It’s not just the food. Eating an excessively large meal, wearing tight clothes, and lying down soon after eating can increase the risk of heartburn. If you’re experiencing persistent heartburn, it’s often linked to diet rather than another factor.

Is heartburn the same as GORD?

No. Heartburn specifically refers to the burning sensation in the chest. GORD is the underlying condition involving the backflow of acid. Heartburn is a symptom of GORD. Acid reflux is sometimes used as shorthand for GORD – however, not every attack of acid reflux is an example of GORD.

Acid reflux refers to any episode of acid backflowing into the oesophagus. If the episodes occur two or more times a week, it is diagnostic for GORD. Most people experience acid reflux episodes occasionally. This can increase in frequency as acid reflux progresses to GORD. You should speak to a doctor if you notice this change.

Does acid reflux always cause heartburn?

Heartburn is always caused by the backflow of acid into the oesophagus. Several other conditions can create a similar sensation. For example:

  • Oesophageal ulcers. Ulcers occur due to erosion of the oesophageal lining. Often associated with acid reflux or overusing anti-inflammatory medications.

  • Oesophagitis. Severe inflammation of the oesophagus is closely linked to GORD. However, it can also be caused by medications and infections. An allergic condition known as eosinophilic oesophagitis can also cause heartburn.

  • Functional heartburn. Unlike the other conditions, this isn’t a problem with your oesophagus or stomach. It’s caused by a disorder of the gut-brain connection. It involves the same heartburn symptoms but without any signs of acid reflux or inflammation. It’s connected to overactive nerves.

How long does heartburn last?

Heartburn is not a permanent condition. It lasts as long as the acid is present to irritate the oesophagus and throat. Most people experience heartburn and GORD for between a few minutes to several hours. The timespan often depends on the underlying cause. For example, if your heartburn is due to your diet, it might go away within a few minutes. In contrast, if you have a hiatus hernia, the heartburn might persist for much longer, even after standing up.

Constant heartburn is a rare symptom. It’s a concerning sign, as the acid can continue to damage your oesophagus. If you’re constantly feeling heartburn (or using lots of antacids), then it’s critical to speak to a doctor.

Is heartburn serious?

Most cases of heartburn aren’t serious. It’s common to experience heartburn after a large meal or eating certain foods. However, if the heartburn becomes repeated or constant, it can cause long-term damage. Usually, the damage caused by acid reflux heals like any injury. If it happens regularly, then the oesophagus lining can become permanently injured.

Potential long-term complications include:

  • Oesophageal strictures. The lining of the oesophagus becomes replaced with scar tissue due to repeated inflammation. This scar tissue causes a narrowing of the oesophagus (stricture), which prevents food from getting through.

  • Intestinal metaplasia. The tissue lining of the oesophagus undergoes a change to look more like the lining of your intestines, protecting it from damage. It is called Barrett’s oesophagus and is a precancerous condition.

  • Oesophageal cancer. Cancer is a rare complication of GORD and heartburn. It occurs due to persistent inflammation and cellular changes. The longer your heartburn persists, the greater the risk of cancer.

Heartburn and GORD can also indicate problems in your stomach. For example, excess acid production can lead to gastritis (stomach inflammation) and stomach ulcers. It may also aggravate preexisting conditions such as asthma.

How do we diagnose the causes of heartburn?

The following tests may be used to diagnose what is causing your heartburn:

  • Oesophageal manometry – which measures the function of your oesophagus (food pipe)

  • 24-hour pH impedance monitoring – which looks at whether you have any reflux

  • Carbohydrate malabsorption breath test – which finds out if you have certain food intolerances (lactose or fructose)

  • Small intestinal bacterial overgrowth (SIBO) breath test – which finds out if you have an overgrowth of bacteria in your small intestine (called SIBO)

  • Gastric emptying test – which measures how quickly food leaves your stomach

    The following tests may be used to diagnose what is causing your heartburn:

  • Oesophageal manometry – which measures the function of your oesophagus (food pipe)

  • 24-hour pH impedance monitoring – which looks at whether you have any reflux

  • Carbohydrate malabsorption breath test – which finds out if you have certain food intolerances (lactose or fructose)

  • Small intestinal bacterial overgrowth (SIBO) breath test – which finds out if you have an overgrowth of bacteria in your small intestine (called SIBO)

  • Gastric emptying test – which measures how quickly food leaves your stomach

Heartburn treatment

Lifestyle changes

Most people who experience occasional heartburn symptoms can benefit from lifestyle changes. This involves limiting exposure to potential triggers. You might want to try:

  • Avoiding trigger foods, such as fatty foods or caffeinated beverages

  • Eating smaller meals

  • Avoiding tight clothing

  • Avoiding lying down immediately after eating

  • Quitting smoking and alcohol consumption.

Often, people find that small changes to their diet can stop or reduce episodes of heartburn. If the heartburn continues, it’s usually a sign that something else is going on. It’s crucial to get to the bottom of your symptoms; otherwise, they will persist.

Medication

As heartburn is caused by acid, neutralising this acid relieves symptoms. The primary treatment for heartburn is an over-the-counter (OTC) antacid, such as Gaviscon or Alka-Seltzer. These medications provide immediate relief from your symptoms – perfect for tackling a sudden acid reflux attack. If you experience constant heartburn, it’s sensible to carry antacids with you. However, excessive use of antacids can cause other problems.

Your doctor may prescribe medications that prevent acid production. This includes:

  • Proton Pump Inhibitors (PPIs). These medications reduce stomach acid production by blocking the enzyme in the stomach lining that produces acid. Common examples include omeprazole, esomeprazole, and pantoprazole. PPIs are used to treat GORD by allowing the oesophagus to heal and preventing further damage.

  • H2 Receptor Antagonists. These drugs work by blocking H2 receptors on stomach cells that signal the production of acid. This results in decreased stomach acid output. Examples include ranitidine, famotidine, and cimetidine. They are effective in relieving GORD symptoms and are generally used for milder cases.

Surgery

In the majority of cases, lifestyle changes and medication are enough to prevent heartburn symptoms. If GORD doesn’t respond to medication, surgery might be a potential option. This can repair a hiatus hernia, strengthening the lower oesophageal sphincter and permanently preventing the backflow of acid.

Procedures include:

  • Nissen fundoplication. This procedure tightens the junction between the stomach and the oesophagus.

  • Transoral incisionless fundoplication. A similar procedure performed non-surgically using an endoscope.

  • LINX device. A tiny ring of magnets is placed around the junction between the stomach and oesophagus to prevent reflux. It’s a type of minimally invasive surgery.

When should you seek medical care for heartburn?

Heartburn is extremely uncomfortable. However, most cases are relatively mild and treatable with antacids. Speak to a medical professional if:

  • You experience heartburn more than once a week

  • You have other associated symptoms

  • You have difficulty swallowing

  • Your heartburn persists despite treatment

  • You’re over the age of 60

  • You have a tight or squeezing chest pain

  • You cough up blood

Remember, occasional heartburn is relatively normal. But if you have constant heartburn, it’s crucial to get tested. The Functional Gut Clinic is highly experienced in diagnosing acid reflux. We’ll organise your test and provide advice on what to do next.

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Are you experiencing any other symptoms

Symptoms are often closely connected. Find out more below.

Reflux

Burning mid-chest, worse when bending or lying down

Constipation

Difficulty going to the toilet, unusual stools, often with stomach ache or intestinal cramps, bloating, nausea or appetite loss

Bloating

Feeling uncomfortably full and tight, excess belching/breaking wind, abdominal pain or gurgling

Regurgitation

Bringing food or drink back up, difficulty swallowing, feeling that food or drink is stuck in your throat, horrible taste in your mouth

Swallowing Issues

Dysphagia - difficulty swallowing, feeling that food or drink is stuck in your throat, horrible taste in your mouth

Diarrhoea

Loose or explosive stools, can’t get to a toilet in time

Abdominal Pain

Cramps; sharp or dull pain, Bloating, Excessive belching, Nausea or vomiting

Faecal Incontinence

Stools leak unexpectedly, Can’t get to a toilet in time

IBS

Abdominal pain or cramping, bloating, changes in bowel habits and urgency, gas